Milk Thistle Extract Silymarin

Product Introduce

Product Name: Milk Thistle Extract

Main ingredient: Silymarin

CAS No.: 65666-07-1

Formula: C25H22010

Appearance: Yellow or brown powder

Milk Thistle Extract (Silymarin Powder), a potent Health food ingredient and Herb extract, is a flavonoid lignan component derived from Milk Thistle. Currently, the total flavonoid lignan content in silymarin preparations like Ligalon and Yiganling is approximately 80%. These preparations primarily consist of four isomers: silybin (silybin A and silybin B), isosilybin, silychristin, and silydianin, with silybin being the most abundant and exhibiting the highest liver protection activity.

Function

Silymarin demonstrates multiple beneficial effects, including its ability to inhibit lipoxygenase and peroxidase. Clinically, it is utilized for the treatment of liver poisoning, liver dysfunction, anti-radiation therapy, and hypolipidemia. Extensive research has revealed that silymarin and its silybin compounds possess a wide range of pharmacological activities:

Removal of Reactive Oxygen Species

Silymarin acts as a powerful antioxidant, directly eliminating reactive oxygen species, combating lipid peroxidation, and maintaining the fluidity of cell membranes. This property makes it an attractive Nutritional Supplement for those seeking to support their body's natural defense mechanisms against oxidative stress.

Liver Protection

Silymarin exhibits a protective effect against liver damage caused by various hepatotoxins such as carbon tetrachloride, galactosamine, and alcohols. Its potent hepatoprotective properties make it a valuable Food Additive and Chinese herb extract for individuals looking to support liver health.

Anti-Tumor Effect

Numerous active oxygen species can oxidize DNA bases, forming 8-oxo-guanine, which leads to DNA damage and potentially tumors. The application of antioxidants, particularly free radical scavengers like silymarin, can prevent the occurrence of this process, thus contributing to its potential anti-cancer properties.

Anti-Cardiovascular Disease Effect

Ksoottva et al. studied the oxidation effect of milk thistle extract on high cholesterol and low-density lipoprotein (LDL) in mice. Mice fed with polyunsaturated fatty acids and a small amount of saturated fatty acids from aqueous fermin extract, which contains silymarin, showed a significant decrease in serum cholesterol content compared to mice fed with polyunsaturated fatty acids and a small amount of saturated fatty acids without the extract. This reduction in very-low-density lipoprotein (VLDL) levels suggests that silymarin may have a cardioprotective role and could be used as a dietary supplement to support cardiovascular health.

In conclusion, silymarin, a versatile and potent bioactive compound found in plants like Milk Thistle, offers a myriad of health benefits spanning from liver protection and antioxidant activity to potential anti-tumor and cardiovascular disease prevention properties. As a result, it is increasingly incorporated into various Nutritional Supplements, Health food ingredient, Herb extract, Food Additive, and Chinese herb extracts to promote overall wellness and support specific health concerns.